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Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB Size:100mg PEG3 linker enhances water solubility

SKU 10276015993
4.5
USD195.00 USD235.00

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Ships within 48 hours · Estimated delivery Aug 4 - Aug 9

Description

PEG3 linker enhances water solubility and provides spatial separation to minimize steric hindrance during binding interactions

Product Name Thalidomide-C3-PEG4-C2-Br Synonyms Thalidomide-4'-C3-PEG4-C2-Br CAS Number n/a Related CAS Molecular Formula C26H35BrN2O9 Molecular Weight 599

DOTA bifucational chelator containing an azide group

a novel and potent GSPT1 degrader displaying selectivity over 9000 proteins

It can be used to label proteins

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB Size:100mg PEG3 linker enhances water solubilitySOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine

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